LCNP 004: Nootropic Stacking – Reasons, Strategies, and Suggestions

In this episode of the Cortex nootropics podcast, we’re going to talk about stacking strategies for smart drugs and nootropics. We’ll discuss:

  1. Stacking choline sources with racetams, and why.
  2. The potential depletion of acetylcholine when using certain racetams.
  3. Preventing racetam headaches via ensuring optimal acetylcholine levels.
  4. Stack suggestions like ALCAR and Bacopa, CDP Choline and Triacetyluridine, Aniracetam and Alpha GPC, Theanine and Caffeine, and more.

As I promised in the podcast, here are the official names of the Shankhpushpi nootropic stack:Convulvulus pluricaulis Choisy. (Convulvulaceae), Evolvulus alsinoides Linn. (Convulvulaceae), Clitoria ternatea Linn. (Papilionaceae) and Canscora decussata Schult. (Gentianaceae).

Links mentioned/talked about

  1. Piracetam and cholinergic transmission – Longecity
  2. Dave Asprey/Steven Fowkes’ coining of the term “Choline Dominant.” 
  3. CDP Choline increases ACh and dopamine receptor densities – Longecity
  4. An update on Shankhpushpi: a cognition-boosting Ayurvedic medicine – Pubmed
  5. Cortex Gen 1 nootropic stack
  6. CDP Choline – A pharmacological review – Pubmed
  7. Reduced lipofuscin accumulation in senescent rat brain by long-term acetyl-L-carnitine treatment – Pubmed

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