Cortex Nootropic Stack (Gen 1)
- Science Behind the Ingredients
The Cortex Nootropic is a novel nootropic stack that combines the power nootropic Uridine Monophosphate with CDP Choline, Artichoke Extract, and Bacopa Monnieri, designed to improve mental performance.
This unique compound acts as a nootropic in and of itself. It brings with it the capacity to induce neurite outgrowth and enhanced creation of phosphatidylcholine, two major components of fluid, optimized brain function. Uridine also positively modulates dopamine receptors, providing a powerful motivating effect.
CDP, otherwise known as Citicoline, is a unique compound that acts both as a precursor to acetylcholine, which is a neurotransmitter that facilitates focus and attention, and as a positive dopamine modulator, functioning to improve motivation.
This compound is a great complimentary nootropic, within the Cortex stack.Â The main proposed mechanism of action is the inhibition of an enzyme in the brain that breaks down cyclic adenosine monophosphate, or cAMP, called PDE4. It is thought that more cAMP in the brain promotes a state of focus and energy.
An ages old adaptogenic herb, Bacopa fits nicely within the Cortex nootropic stack. Adaptogenic herbs, like Bacopa, have been demonstrated to promote axon and dendrite growth within the brain, as well as aid in helping the body and brain deal with incoming stress.
Ingredients + Science
Working memory + verbal fluency
One of the most powerful ingredients in our formula is Uridine Monophosphate. We wanted both the uniqueness and the raw horse power of this amazing ingredient in our Nootropic Stack. Being both a facilitator of the synthesis of Phosphaditylcholine, a major component of the cell membrane of the brain's neurons, and an aid in synaptic functioning of the brain, Uridine Monophosphate is a nootropic in and of itself.
Uridine Monophosphate has been shown to influence what's called "neurite growth" in the human brain. Neurites are projections from brain neurons, which can either be axons or dendrites. The brain becomes functionally better by branching neurons together, through these axons and dendrites. Combined with CDP-Choline, Uridine has the potential to increase brain phosphatidylcholine in a major way, and facilitate great brain functioning that results in improved focus, mental energy, and working memory.
Brahmi (Bacopa Monnieri)
Brahmi is one of the most well known, and historically relevant nootropics known to man. The significance of this nootropic stems from the class of medicine called "Ayurveda," with historical roots in the Indian subcontinent. Specifically, Brahmi packs a powerful punch being an adaptogen (a compound that helps the body adapt to stress), a cognitive support mechanism by way of reducing anxiety, and a facilitator of memory formation.
In addition to its powerful memory enhancing effects, Brahmi has been shown to mildly effect Acetylcholine levels, increasing them, creating a great synergy with the Uridine Monophosphate, and CDP Choline in our stack. Astonishingly, it has also been proven as an agent of neuro-protection (section 3.9), reducing oxidative damage from aluminum, mercury and others, and preventing cognitive ion overloads.
But perhaps the most significant factor in Brahmi's arsenal is the fact that it's neuro-anti-inflammatory, and may exert an anti neurological aging effect as a result of what are called "bacosides." That's pretty impressive, for an herbal compound. It has both acute, and long term positive effects on brain function, and goes well with the other elements in the Cortex Nootropic stack.
Adaptogenic stress inhibition
Mental energy + concentration
This nutrient has taken the nootropic world by storm over the last few years. Mixed with Forskolin, it's purported to be one of the strongest nootropics there is. But we found something interesting out: It's extremely synergistic with the rest of our stack, particularly the nutrients that work on the Cholinergic system of the brain.
The main proposed mechanism of action is the inhibition of an enzyme in the brain that breaks down cyclic adenosine monophosphate, or cAMP, called PDE4. It is thought that more cAMP in the brain promotes a state of focus and energy. But the interesting part about Artichoke extract is that Luteolin, a major component of AE, has been shown to induce neurite outgrowth. The rest of this stack, particularly the Uridine monophosphate, is also targeted at inducing neurite outgrowth. This partially is likely responsible for the synergy in the stack between these ingredients, and the beneficial reported effects from the Cortex beta testers.
And here's the great part: It doesn't need to be stacked with Forskolin to get the major benefits. Artichoke Extract is a nootropic in its own right, and synergizes well with the rest of the Cortex nootropic stack.
The Cortex Gen 1 stack focuses on enhancing the building and synthesis of the neurotransmitter Acetylcholine. A major constituent and extremely bioavailable precursor to this neurotransmitter is CDP Choline. But that isn't what's really important here. The significance of this nutrient, is it's role in creating phosphatidylcholine, a major component of the cell membranes of the neurons in the human brain. The science points to the major benefits of combining Uridine Monophosphate with CDP Choline, which improves the synthesis of CDP Choline in the brain, which is the immediate precursor to phosphatidylcholine.
The major revelation that we had in creating this stack, is that Uridine and CDP-Choline, while interesting nootropics in and of themselves, create an intense nootropic experience when put together in a nootropic stack. It is thought that the combination of Uridine Monophosphate, and CDP-Choline, help increase both Nerve Growth Factor, and boost levels of brain phosphatidylcholine, and important element of the neuron's cell membrane.
Intense focus + motivation
What You Can Expect From The Cortex Nootropic Stack
Speed Of Processing
You can sum up some of the most powerful effects of this Nootropic stack in one word: Speed. There is no denying, in all of the people who have tried Cortex Gen 1, that speed of mental processing and enhancement in verbal fluency are major benefits of this stack.
Originating from the feedback of some of the first samplers of Cortex, we believe there is a type of neuronal fluidity taking place that is making this speed of processing possible. The number one report in this regard about Cortex is a striking increase in performance in the ability to form sentences, deliver speech and access words with extreme ease, as well as retrieve important information from long term and working memory. It's as if all of these functions become effortless and smooth while Cortex does its work. We are heavily researching the exact mechanisms of this phenomenon, and are working on getting some detailed scientific studies to back what anecdotally, we already know.
Motivation and Mental Energy
This stack was designed with performance in mind. The real workhorses of this nootropic stack, Uridine monophosphate and CDP Choline, provide an exceptionally smooth amount of mental energy in users. The dopamine effect from both of these compounds provides an extremely motivating response that can help users get right to work on engaging in the things that matter.
Great nootropic stacks should provide the brain with the raw materials it needs to engage in productive work. Mental energy and motivation are predictable byproducts of supplying the brain with such materials, and in this context, Cortex generation 1 delivers. Our early adopters and regular customers can attest to motivation and mental energy the Cortex Gen 1 stack delivers.
Focus Endurance And Memory
Another standout effect that users of Cortex report is what can be called focus endurance. Normally, focus is quite finite. You might be able to sit down for a half hour to an hour and give your undivided attention to a task.
Focusing is a vital part of the human experience. It allows us to be in the moment. It allows us to put forth 100% of our efforts into a worthwhile task to be the effective entrepreneurs, executives, and elite achievers we all want to be. The ingredients in cortex help facilitate the ability to focus for long sessions at a time, without losing your mental stamina.
The Cortex Gen 1 nootropic also delivers a powerful short term and working memory effect that appears consistent in all of the early adopters/test subjects we've used to sample the product. It is also hypothesized that the increase in neurite growth and optimization of the brain chemical Acetylcholine, facilitated by all 4 of the chemicals in this nootropic stack, are responsible for these powerful effects.
Customer Reviews on the Cortex Stack
This supplement actually works! I usually have a hard time coming up with the right thing to say and this Cortex supplement somehow makes my brain able to find the right words without trying. I've tried lots of other nootropics. Piracetam and Aniracetam, and the effects were a lot more subtle than Cortex. I mix this with morning coffee and I'm set for the day
I replaced my morning coffee with this stuff! My only qualm is that I spend more with Cortex than I did with Coffee. But I'm a lot more productive at work and oddly more outgoing.
I tried Aniracetam recently and didn't notice anything. I almost gave up on smart drugs but this Cortex stack is definitely noticeable. Not like coffee, just puts me in a productivity mode where I can get a lot of things done. Took me out of a slump! Will buy another bottle
I took the stack at 10AM and within about 40 minutes I finally had the mental energy to tackle a bunch of work related tasks I had been putting off. This is like a productivity supplement. Words flow a lot smoother too. Really enjoyed it.
Love the product but would love a subscription service. I'd take this everyday if there was a condensed 30 day supply option. Cortex gives me a profound wakefulness and concentration ability that I just cannot achieve otherwise. I am times more productive while using the stack.